Laboratory of Genetic Engineering and Methylomic Research
RESEARCH
- Development of new plasmid vectors for expression of functional proteins in prokaryotic and eukaryotic systems
- Creation and study of ways for the practical implementation of engineered recombinant fusion proteins based on thermotolerant domains from various biological sources
- Analysis of specific DNA methylation status of regulatory regions and exons of genes that encode follistatin-like proteins and key participants in the nitrogen metabolism
- Screening and verification of molecular genetic markers associated with a number of pathophysiological processes
- Federal State Budgetary Scientific Institution «I.Mechnikov Research Institute of Vaccines and Sera»
- I.M. Sechenov First Moscow State Medical University
- Federal State Institution «Federal Research Centre «Fundamentals of Biotechnology» of the Russian Academy of Sciences»
Kasap E.Y., Parfenova О.K., Kurkin R.V., Grishin D.V. (2023) Bioinformatic analysis of the coding region of the melatonin receptor 1b gene as a reliable DNA marker to resolve interspecific mammal phylogenetic relationships, Mathematical Biosciences and Engineering, 20(3), 5430-5447. DOI:10.3934/mbe.2023251
Furalyov V.A., Kukes V.G., Gazdanova A.А., Parfenova O.K., Sidorov N.G., Kurkin R.V. (2023) Study of the Protective Properties of 2-Ethyl-6-Methyl-3-Hydroxypyridine Malate in the Model of In vitro-Induced Oxidative Stress in Myoblast Cell Culture, Current Bioactive Compounds, 19(6), e221122211123. DOI:10.2174/1573407219666221122122346
Parfenova O.K., Kukes V.G., Grishin D.V. (2021) Follistatin-Like Proteins: Structure, Functions and Biomedical Importance, Biomedicines, 9(8), 999. DOI:10.3390/biomedicines9080999
Grishin D.V., Kasap E.Y., Izotov A.A., Lisitsa A.V. (2020) Multifaceted ammonia transporters, All life, 13(1), 486-497. DOI:10.1080/26895293.2020.1812443
Kasap E.Y., Grishin D.V. (2020) To a Question on the Mechanism of the Antimicrobial Action of Ortho-Benzoic Sulfimide, Pharmaceuticals, 13(12), 461. DOI:10.3390/ph13120461
Zhdanov D.D., Gladilina Y.A., Pokrovsky V.S., Grishin D.V., Grachev V.A., Orlova V.S., Pokrovskaya M.V., Alexandrova S.S., Plyasova A.A., Pokrovsky V.S., Sokolov N.N. (2019) Endonuclease G modulates the alternative splicing of deoxyribonuclease 1 mRNA in human CD4+ T lymphocytes and prevents the progression of apoptosis, Biochimie, 157, 158-176. DOI:10.1016/j.biochi.2018.11.020
Grishin D.V., Samoilenko V.A., Gladilina Yu.A., Zhdanov D.D., Pokrovskaya M.V., Aleksandrova S.S., Pokrovsky V.S., Sokolov N.N. (2019) Effect of Heterologous Expression of Chemotaxis Proteins from Genus Thermotoga on the Growth Kinetics of Escherichia coli Cells, Bulletin of Experimental Biology and Medicine, 167(3), 375-379. DOI:10.1007/s10517-019-04530-z
Grishin D.V., Zhdanov D.D., Pokrovskaya M.V., Sokolov N.N. (2019) D-amino acids in nature, agriculture and biomedicine, Frontiers in Life Science, 13(1), 11-22. DOI:10.1080/21553769.2019.1622596
Stepanov A.A., Luzgina N.G., Rusanov A.L., Fedoronchuk T.V., Kamenskiy P.A., Ivanov R.A., Malsagova K.A., Grishin D.V., Kaysheva A.L. (2019) Genome editing: current development trends, Clinical Practice in Pediatrics, 14(3), 13-21. DOI:10.20953/1817-7646-2019-3-13-21
Grishin D.V., Gladilina J.A., Zhdanov D.D., Pokrovskaya M.V., Toropygin I.Y., Aleksandrova S.S., Pokrovskiy V.S., Sokolov N.N. (2019) Preparation and Characterization of a New Mutant Homolog of the Chemotaxis Protein CheY from the Anaerobic Hyperthermophilic Microorganism Thermotoga Naphthophila, Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 13(3), 244-255. DOI:10.1134/S1990750819030041
Grishin D.V., Zhdanov D.D., Gladilina Ju.A., Pokrovskaya M.V., Aleksandrova S.S., Sokolov N.N. (2019) Heterogeneous expression and characterization of a new mutant DNA-binding protein from the Thermotoga naphthophila hyperthermophilic microorganism, Proceedings of universities. Applied chemistry and biotechnology, 9(2), 288-301. DOI:10.21285/2227-2925-2019-9-2-288-301