Laboratory of Pharmacoproteomics

Aleksey E. Medvedev Head of Lab
D.Sc., Professor

CONTACTS

+7 (499) 245-05-09

Valerij I. Fedchenko Ph.D.

Olga A. Buneeva Ph.D.


Ludmila N. Aksenova

Svetlana A. Kaloshina

avatar none  Buneeva O., Medvedev A. (2024) Ubiquitin Carboxyl-Terminal Hydrolase L1 and Its Role in Parkinson`s Disease, International Journal of Molecular Sciences, 25(2), 1303. DOI:10.3390/ijms25021303

avatar none  Buneeva O.A., Kopylov A.T., Medvedev A.E. (2023) Proteasome Interactome and Its Role in the Mechanisms of Brain Plasticity, Biochemistry (Moscow), 88(3), 319-336. DOI:10.1134/S0006297923030033

avatar none  Buneeva O., Kopylov A., Gnedenko O., Medvedeva M., Veselovsky A., Ivanov A., Zgoda V., Medvedev A. (2023) Proteomic profiling of mouse brain pyruvate kinase binding proteins: a hint for moonlighting functions of PKM1?, International Journal of Molecular Sciences, 24(8), 7634. DOI:10.3390/ijms24087634

avatar none  Fedchenko V.I., Morozevich G.E., Medvedev A.E. (2023) The effect of renalase-derived peptides on viability of HepG₂ and PC3 cells, Biomeditsinskaya Khimiya, 69(3), 184-187. DOI:10.18097/PBMC20236903184

avatar none  Fedchenko V.I., Veselovsky A.V., .Kopylov A.T, Medvedev A.E. (2023) The search for potential hypotensive peptides in the amino acid sequence of human renalase and their identification in proteolytic fragments of this protein, Biomeditsinskaya Khimiya, 69(6), 403-408. DOI:10.18097/PBMC20236906403

avatar none  Buneeva O.A., Kopylov A.T., Zgoda V.G., Gnedenko O.V., Kaloshina S.A., Medvedeva M.V., Ivanov A.S., Medvedev A.E. (2022) Comparative analysis of proteins associated with 26S and 20S proteasomes isolated from rabbit brain and liver, Biomeditsinskaya Khimiya, 68(1), 18-31. DOI:10.18097/PBMC20226801018

avatar none  Buneeva O., Medvedev A. (2022) Atypical Ubiquitination and Parkinson’s Disease, International Journal of Molecular Sciences, 23(7), 3705. DOI:10.3390/ijms23073705

avatar none  Medvedev A., Buneeva O. (2022) Tryptophan Metabolites as Mediators of Microbiota-Gut-Brain Communication: Focus on Isatin, Frontiers in Behavioral Neuroscience, 16, 922274. DOI:10.3389/fnbeh.2022.922274

avatar none  Fedchenko V.I., Veselovsky A.V., Kopylov A.T., Kaloshina S.A., Medvedev A.E. (2022) Renalase may be cleaved in blood. Are blood chymotrypsin-like enzymes involved?, Medical Hypotheses, 165, 110895. DOI:10.1016/j.mehy.2022.110895

avatar none  Buneeva O.A., Medvedev A.E. (2021) DJ-1 Protein and Its Role in the Development of Parkinson’s Disease: Studies on Experimental Models, Biochemistry (Moscow), 86(6), 627-640. DOI:10.1134/S000629792106002X

avatar none  Buneeva O., Kopylov A., Kaloshina S., Zgoda V., Medvedev A. (2021) 20S and 26S proteasome-binding proteins of the rabbit brain: A proteomic dataset, Data in Brief, 38, 107276. DOI:10.1016/j.dib.2021.107276

avatar none  Medvedev A., Kopylov A., Fedchenko V., Buneeva O. (2020) Is renalase ready to become a biomarker of ischemia?, International Journal of Cardiology, 307, 179. DOI:10.1016/j.ijcard.2019.09.045

avatar none  Medvedev A., Kopylov A., Buneeva O., Kurbatov L., Tikhonova O., Ivanov A., Zgoda V. (2020) A Neuroprotective Dose of Isatin Causes Multilevel Changes Involving the Brain Proteome: Prospects for Further Research, International Journal of Molecular Sciences, 21(11), 4187. DOI:10.3390/ijms21114187

avatar none  Buneeva O., Fedchenko V., Kopylov A., Medvedev A. (2020) Mitochondrial Dysfunction in Parkinson’s Disease: Focus on Mitochondrial DNA, Biomedicines, 8(12), 591. DOI:10.3390/biomedicines8120591

avatar none  Medvedev A., Buneeva O., Gnedenko O., Ershov P., Ivanov A. (2018) Isatin, an endogenous nonpeptide biofactor: A review of its molecular targets, mechanisms of actions, and their biomedical implications, Biofactors, 44(2), 95-108. DOI:10.1002/biof.1408

avatar none  Kopylov A.T., Fedchenko V.I., Buneeva O.A., Pyatakova N.V., Zgoda V.G., Medvedev A.E. (2018) A new method for quantitative determination of renalase based on mass-spectrometry determination of a proteotypic peptide labeled with stable isotopes, Rapid Communications in Mass Spectrometry, 32(15), 1263-1270. DOI:10.1002/rcm.8167

avatar none  Buneeva O., Kopylov A., Kapitsa I., Ivanova E., Zgoda V., Medvedev A. (2018) The effect of neurotoxin MPTP and neuroprotector isatin on the profile of ubiquitinated brain mitochondrial proteins, Cells, 7(8), 91. DOI:10.3390/cells7080091